| Titre : | Etude phytochimique et activité biologique d'extait de des feuilles de phoenix dactylifera L dans la région du sud d'algérie(la région d'oued souf) |
| Auteurs : | salaheddine Laouini, Auteur ; segni Ladjel, Directeur de thèse |
| Type de document : | Monographie imprimée |
| Editeur : | Biskra [Algerie] : Université Mohamed Khider, 2014 |
| Format : | 216p / 30CM |
| Langues: | Français |
| Mots-clés: | Phoenyx dactylifera L,leaves,Polyphenols,DPPH,Antidiabetic,Anti- inflammatory,antimicrobial,south Algeria. |
| Résumé : |
The date palm (
Phoenyx dactylifera L ) consisted, for the people of southern Algeria, as tree of providence. Dates and their extracts are also used for many centuries as a medicine against allergy, inflammation, constipation and gastro prot ective; they also have a high antibacterial and antioxidant activity. However, no studies are c onducted to evaluate the extract from the leaves of date palm ( Phoenyx dactylifera L) in point of view pharmacology effect. In this study we have evaluated the phytochemical compositi on, antioxidant antibacterial, antifungal and antimutagenic properties and anti-inflammatory properties determined by measuring the inhibition of nitric oxide (NO) production of leave s extract of three varieties Ghars, Deglet Nour and Hamraya from Phoenyx dactlylifera L. Moreover, the antidiabetic effect was evaluated by inhibition of α -amylase and α -glucosidase enzymes. According to the results, the extracts have very important values for polyphenols , flavanoids, flavonols, condensed tannin, anthocyanin and high antioxidant activity against D PPH, FRAP, ABTS, OH · . Also the three extracts reveal a considerable antimicrobial potenc y and antifungal considerable activity. The three varieties exhibited significant anti-inflamma tory effects using in-vitro inhibition of NO, exhibited potent antimutagenic high inhibitory level of the Ames response induced by the indirect mutagen 2- aminoanthracene and also displayed high inhibition actions agains t α - amylase and α -glucosidase enzymes. The results suggest that the leaves of the three selected varieties of Phoenyx dactylifera L can be considered as a good source of natural an tioxidant, antimicrobial and anti-inflammation drugs as well a s potent antidiabetic medicine. |
| Type de document : | Thése doctorat |
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| Cote | Support | Localisation | Statut | Emplacement | |
|---|---|---|---|---|---|
| TH/0523 | Thèse de doctorat | BIB.DEP.ARCHITECTURE | Sorti jusqu'au 20/02/2021 | Salle de mémoires et de théses |
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