Etude phytochimique et activité biologique d'extait de des feuilles de phoenix dactylifera L dans la région du sud d'algérie(la région d'oued souf) [texte imprimé] / salaheddine Laouini, Auteur ; segni Ladjel, Encadreur . - Biskra (B.P.145,R.P., 07000, Algerie) : Université Mohamed Khider, 2014 . - 216p ; 30CM. Langues : Français ( fre) Mots-clés : | Phoenyx dactylifera
L leaves Polyphenols DPPH Antidiabetic Anti-
inflammatory antimicrobial south Algeria. | Résumé : | The date palm (
Phoenyx dactylifera
L
)
consisted, for the people of southern Algeria, as
tree of
providence. Dates and their extracts are also used
for many centuries as a medicine against
allergy, inflammation, constipation and gastro prot
ective; they also have a high antibacterial
and antioxidant activity. However, no studies are c
onducted to evaluate the extract from the
leaves of date palm (
Phoenyx dactylifera
L) in point of view pharmacology effect. In this
study we have evaluated the phytochemical compositi
on, antioxidant antibacterial, antifungal
and antimutagenic properties and anti-inflammatory
properties determined by measuring the
inhibition of nitric oxide (NO) production of leave
s extract of three varieties Ghars, Deglet
Nour and Hamraya from
Phoenyx dactlylifera
L. Moreover, the antidiabetic effect was
evaluated by inhibition of
α
-amylase and
α
-glucosidase enzymes. According to the results, the
extracts have very important values for polyphenols
, flavanoids, flavonols, condensed tannin,
anthocyanin and high antioxidant activity against D
PPH, FRAP, ABTS, OH
·
. Also the three
extracts reveal a considerable antimicrobial potenc
y and antifungal considerable activity.
The
three varieties exhibited significant anti-inflamma
tory effects using in-vitro inhibition of NO,
exhibited potent antimutagenic
high inhibitory level of the Ames response induced
by the
indirect mutagen 2- aminoanthracene
and also displayed high inhibition actions agains
t
α
-
amylase and
α
-glucosidase enzymes. The results suggest that the
leaves of the three selected
varieties of
Phoenyx dactylifera
L can be considered as a good source of natural an
tioxidant,
antimicrobial and anti-inflammation drugs as well a
s potent antidiabetic medicine.
| Type de document : | Thése doctorat |
|